Conn’s Syndrome: A Diagnostic Dilemma

Tuesday, 01 March 2011 02:17
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Conn’s Syndrome: A Diagnostic Dilemma. Case Report


Conn’s syndrome or primary hyperaldosteronism is characterized by hypertension, hypokalemia and increased ratio of plasma aldosterone concentration (ng/dl) to plasma renin activity (ng/ml per hour). Primary aldosteronism occurs most commonly due to aldosterone producing adenoma (Conn’s syndrome) or bilateral adrenal hyperplasia. The clinical manisfestation may be varied. We report an atypical neurological presentation of primary aldosteronism due to an aldosterone-producing adenoma.




Primary aldosteronism is characterized by hypertension, hypokalemia, suppressed renin activity and increased aldosterone excretion and was first described by J. W. Conn in 19551. Primary aldosteronism used to be considered as a rare form of hypertension but it is now recognized to be the most common form of secondary hypertension with prevalence estimates of 5-13% of all patients with hypertension 2,3. Primary aldosteronism occurs most commonly due to aldosterone-producing adenoma (Conn’s syndrome) or bilateral idiopathic hyperplasia and less commonly due to primary (unilateral) adrenal hyperplasia, aldosterone-producing adrenocortical carcinoma or familial hyperaldosteronism4.

Last Updated ( Saturday, 30 April 2011 10:53 )

patient underwent surgical resection of mass / Pictures

Tuesday, 11 January 2011 11:06
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54 yr old male presented with RUQ pain , CT scan showed large round mass, patient underwent surgical resection of mass , an pathologic evaluation is under investigation.

Last Updated ( Friday, 27 May 2011 08:26 )

Burning due gas explosion / Pictures

Monday, 03 January 2011 18:36
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45 yr old male with grade 4 burning, due to gas explosion in his house, burning injury to his leg and inhalation injury to his lung was very severe and the patient admitted to ICU.

Last Updated ( Friday, 27 May 2011 08:25 )

Destruction of both hip joints / Pictures

Saturday, 04 September 2010 18:36
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4 yr old boy with past history of bilateral hip septic arthritis, presented with waddling gait 6 months after treatment.

Pelvic x-rays and MRI showed marked destruction of both hip joints.

Patient underwent osteotomy for right hip and another surgery for left hip was planned after recovery.

Last Updated ( Friday, 27 May 2011 08:25 )


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